一、个人简介
何丹，女，博士，副教授，硕士生导师，执业药师，重庆药学会药剂专业委员会主委委员。重庆医科大学药学院药物分析学系教师。负责/主研多项课题，包括国家科技支撑计划子课题1项，重庆市教委科学技术项目4项，重庆市人力资源和社会保障局项目1项和多项横向项目；以第一/通讯发表SCI收录论文31篇，第一/通讯发表CSCD/中文核心期刊收录论文42篇；获国家发明专利9项；获省部级自然科学奖三等奖一项，获美国药学会优秀论文奖。副主编专著1部，参编国家规划教材5部；参与制药企业标准评审8项；西北药学杂志青年编委，Phytomedicine，TALANTA，Journal of Food Measurement and Characterization等杂志审稿专家。
二、研究方向
中药质量评价和药效物质基础研究
三、代表性成果
承担项目：
1. 基于 PI3K/AKT/mTOR 信号通路麝香抗小细胞肺癌的作用机制研究，（CY200412），2024重庆市教委，2024.10-2026.06，主持
2. GC-MS法测定血浆中脂肪酸含量，横向课题，2024.06-2024.12
3. SX样品GC-MS代谢组检测，2023.03-2023.06，横向课题
科研论文：
1. Yaxuan Li, Jingqing Zhang, Nanchuan Song, Yiwu Wang , Jialing Yu , Lin He , Ruijia Yang, Lin Yang , Dan He*. Regional variation, water quality, health risk assessment and source analysis ofheavy metals in sewage and tap water in Chongqing municipality. Environmental pollution. 2025,373:126193 DOI:10.1016/j.envpol.2025.126193
2. Shuxiang Pan, Lin Yang, Yiwu Wang, Yuan Shen, Jialing Yu，Dan He*. Exploring potential health risk factors associated with heavy metals in Chenxiang Huaqi Tablets based on inorganic elemental evaluation. Biological Trace Element Research. April,2025. doi.org/10.1007/s12011-025-04642-w
3. ZhiqiXu, Yan Li,Yuan Shen, Yiwu Wang, Jialing Yu, Xinxin Xiang, LinYang*, Dan He*.Determination and comparison of amino acid content of Teminalia Chebula in different origins and different processing states based on microwave digestion. Foods. 2025,14(7):1166, DOI:10.3390/foods14071166
4. Lin Yang,Lei Dai, Weihan Qin, Yiwu Wang, Jianing Zhao, Shuxiang Pan, Dan He*. Geographical discrimination of Quisqualis indica L by UPLC-Q-TOF-MS based on qualitative and quantitative analysis combined with chemometrics.Frontiers in plant science，2024, https://doi.org/10.3389/fpls.2024.1418480
5. Jingxin Xu, Mingjun Wu,Jie Yang, Dezhang Zhao, Dan He, Yingju Liu, Xiong Yan, Yuying Liu, Daojun Pu, Qunyou Tan, Ling Zhang, Jingqing Zhang. Multimodal smart systems reprogram macrophages and remove urate to treat goutyarthritis". Nature Nanotechnology, 2024.07, https://doi.org/10.1038/s41565-024-01715-0
6. Shuya Li, Ke Yin, Yiwu Wang, Lihong Tan, Jianing Zhao, Shuxiang Pan, Lin Yang, Dan He*.Integrating ICP-MS and Chemometrics for Profiling Inorganic Elements in Lianhua Qingwen Capsules and Evaluating Health Risk. Biological Trace Element Research.2024.06, DOI:10.1007/s12011-024-04279-1
7. Lei Dai, Lin Yang, Yiwu Wang, Yan Li, Jianing Zhao, Shuxiang Pan, Yaxuan Li, Dan Yang, Dan He*. An optimized microwave digestion method to analyze the amino acids profile of Quisqualis Fructus from different origins.Foods, 2024,06, DOI: 10.3390/foods13111645
8. Xiaoli Xu, Lin Yang, Dezhang Zhao, Yiwu Wang, Lei Dai, Shuya Li, Dan He*.New Quality Evaluation of Qizhi Xiangfu Pills Based on Fingerprint with chemometric analysis and Quantitative Analysis of Multi-Components by Single Marker. Journal of chromatographic science. 10.1093/chromsci/bmae005 2024.03
9. Wei-han Qin, Jia-jia Zou, Lin Yang, De-zhang Zhao, Yang Yong, Lei Dai, Shu-ya Li, Yan Li, Dan He*. Study on Chemical Differences between the Seeds of Paeonia ludlowii and Oil Peony Based on UPLC-Q-TOF-MS/MS and GC-MS/MS. Journal of Food Measurement and Characterization. DOI: 10.1007/s11694-024-02364-6, 2024,Feb
10. Lei Dai, Yang Lin, Li Yan, Shuya Li, Dan Yang, Yaxuan Li, Dan He*. Origins differentiation based on volatile constituents of genuine medicinal materials Quisqualis indica L via HS-GC-MS, response surface methodology and chemometric. Phytochemical Analysis. DOI：10.1002/pca.3313. 2024 Jan 8
11. Shuya Li, Dezhang Zhao, Yuan Shen, Lei Dai, Weihan Qin, Dan Yang, Yaxuan Li, Lin Yang, Yan Li, Dan He*. Identification of Different Varieties of Oil Peony Seeds Combining ICP-MS with Chemometrics and Assessment of Associated Health Risk. Biological Trace Element Research. DOI：10.1007/s12011-023-03998-1.2023.12.
四、联系方式
E-mail: hedan@cqctcm.edu.cn